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What is Biological buffers?

Biochemical processes are markedly impaired by even small changes in the concentrations of free H+ ions. It is therefore usually required to stabilise the H+ concentration in vitro without affecting the system's functioning. A buffer keeps the pH of a solution constant by taking up protons that are released during reactions, or by releasing protons when they are consumed by reactions. The observation that partially neutralised solutions of weak acids or bases are resistant to changes in pH when small amounts of strong acids or bases are added led to the concept of the ‘buffer’. In the synoptical table, the most common biological buffers are listed according to their optimal buffer range. The table also gives some hints for potential applications and shows advantages or disadvantages of the listed buffer substances.

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Buffer solutions
Buffers A to Z